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Amicus Therapeutics is a Cranbury, New Jersey biopharmaceutical company that has been led by CEO John Crowley since 2005. It has publicly operated since 2007. Amicus primarily does research and development for medicines and treatments of rare and orphan diseases. In particular, they are focused on developing new enzyme replacement therapies. Its most promising drug at present is migalastat, which is a major component for treatment of Fabry Disease. It also has promising drugs in development for Pompe Disease, the skin disorder known as Epidermolysis Bullosa, and various Lysosomal Storage Disorders.

 

It had some measure of financial success in the earliest years, but it was really given a boost in 2010 with two huge grants: $500,000 from The Michael J. Fox Foundation and $210,300 from the Alzheimer’s Drug Discovery Foundation. During that same year, Amicus saw several key changes in leadership: Crowley assumed the role of Amicus Therapeutics Chairman of the Board, David Lockhart became the Chief Scientific Officer, and Brandon Wustman became the Director of Exploratory Biology. From that point forward Amicus Therapeutics kept growing in a big way (YahooFinance).

 

In 2013, it acquired and absorbed Callidus Biopharma, a major competitor (https://www.crunchbase.com/organization/amicus-therapeutics). Then in 2015 it acquired and absorbed Amicus Therapeutics is fully capable of research and development; however, it does not have the facilities or equipment to mass manufacture these drugs on its own. That is why it contracts with manufacturers to do so. However, they are today at the top in the international industry at what they do. But the company intends to seek further frontiers and to explore other ways of bettering itself so that it can in turn better help the world. Above all else, its goal is to create it into a healthier one. Amicus Therapeutics has an abundance of great information and contact details on its website at www.amicusrx.com.

Arthritis is a common disease that is not understood well by all. Over 100 different kinds of arthritis are there. It is a leading problem behind disability in any nation.

 

Osteoarthritis remains the most common form of arthritis. It occurs due to the degeneration of cartilage (https://www.osteoreliefinstitute.com/blog/). Osteo Relief Institute specifies that curing it is not possible. But there are several ways to manage it and improve the quality of life.

 

Typically exercise can be really helpful here. It may be painful to move due to osteoarthritis, but physical activity is critical in order to manage the pain as well as the loss of mobility that is associated with arthritis. This means that the affected persons must force themselves to move daily!

 

Osteo Relief Institute suggests activities which tend to build the muscles around joints. Care has to be taken that there is not too much stress on the joints. This would mean focusing on stretching exercises or those which provide a range-of-motion. Gradually it can lead to progressive strength training.

 

Next are the low-impact aerobic exercises. These can include walking and cycling beside water exercises. These can help to control weight besides improving mood too.

 

Osteo Relief Institute says that activities which may impact on joints or include repetitive motion must be avoided. These would include running, jumping, as well as golf and tennis.

 

Several different medications are available that provide pain relief from arthritis. But all these medications have some side effects when they are taken over a long time. Hence it is best to consult a doctor before starting them.

 

Physical Therapy is an excellent resource as it helps to move the body in a way to minimize the pain as well as mobility loss which is associated with arthritis. Hence committing to physical therapy can be a good option that can help to stay away from surgery.

 

In case the conservative methods fail, the best option may be a surgical one. This can include options such as minimally invasive joint repair, besides joint fusions, as well as joint replacements.

 

There are skilled orthopedic specialists who can provide more information about each option. It can be chosen based on the condition of the patient as well as desired lifestyle.

More at http://www.longislandosteorelief.com/